Relapse of genital herpes: what to do with a repeated diagnosis?
Recurrent genital herpes is an exacerbation of a pathological condition. Once in the human body, the virus remains in it forever, but microorganisms begin active reproduction only under certain conditions.
Reasons for Relapse
Rarely do doctors manage to establish the cause of recurrent genital herpes. There are patients with frequent exacerbations of herpes, in which the body has a sufficient amount of antibodies. This is due to the ability of microorganisms to penetrate into the cells of the nervous system, avoiding the effects of antibodies.
For this reason, the disorder can resume in the body and often bothers the person. Relapse of genital herpes occurs under the influence of the following factors:
- unhealthy diet for a long time,
- stress and overwork
- taking antimicrobials for a long time,
- surgical intervention,
- overheating of the body or hypothermia,
- lack of hemoglobin in the body,
- substance abuse or alcohol abuse,
- inflammation of the internal organs (genital herpes appears when the urethra is damaged),
- parasitization of any microbes in the body,
- living in adverse environmental conditions.
The second and subsequent genital lesions will not have pronounced symptoms.
The main sign of relapse is the appearance of watery rashes. Activation of microorganisms can also occur with repeated infection through domestic, sexual, or blood circulation.
The herpes virus seriously affects the condition of internal organs, therefore, at the slightest discomfort, you should immediately consult a doctor. Each subsequent relapse will aggravate the patient's condition and make the immune system weaker. Against this background, other diseases may appear with irreversible consequences.
Immunologist's advice on treating recurrent genital herpes
To eliminate relapse, complex treatment is used. It should be understood that the suppression of the activity of microorganisms is possible only in the presence of complex therapy. For this purpose, etiotropic medicines are used (they eliminate the causes of the violation), pathogenetic agents (normalize the state of internal organs) and symptomatic therapy.
Etiotropic drugs lead to the death of the virus, they reduce the number of bacteria in the body and suppress the main symptoms of the disorder. A mandatory component is capsules for oral use. Among them, zovirax, cyclovax, acivir, etc. are popular. In some cases, drugs based on lysine are effective. For local treatment of the affected areas, ointment acyclovir or zorirax is recommended. The mucous membranes are treated with fucorcin.
Genital herpes negatively affects the condition of internal organs, so the doctor selects drugs that can normalize the condition of internal organs and human systems. These medications can reduce the duration of therapy and increase the effectiveness of essential drugs. It is also necessary to adhere to the main recommendations that will help significantly reduce the number of relapses or completely prevent them:
- Reception of immunomodulators. If the virus has managed to reduce the activity of the immune system, then appropriate drugs are prescribed. Preference is given to herbal medicines. With advanced genital herpes or the presence of complications, polyxidonium or amexin is recommended.
- Normalization of metabolism. In the presence of diabetes mellitus, it is mandatory to take drugs that reduce the amount of the harmful component in the blood, in extreme cases, insulin is prescribed.
- Regulation of the hormonal background. For this, special medicines are used after a diagnostic examination.
- Compliance with the main recommendations for strengthening the body. This includes full sleep, proper nutrition and prevention of overwork.
Symptomatic therapy is aimed at improving the current condition of the patient. To reduce itching, allergy medications are prescribed for local or internal use.
Extensive inflammation accompanied by burning is treated with non-steroidal drugs. Bubbles with liquid are treated with special ointments, but it is impossible to accelerate the healing time. It is necessary to wait until they themselves pass and in no case try to open them.
Relapse of genital herpes before childbirth: what to do
When a relapse of genital herpes occurs before childbirth, emergency therapy is performed. Symptoms of a viral disease in the second and third trimester of pregnancy adversely affect the condition of the future mother and child.
If a woman wants to give birth in a natural way, then before that it is necessary to take a course of antiviral medications, otherwise the baby will become infected from the first days of life.
Most often, the main component of therapy is valaciclovir. For some patients, doctors recommend resorting to a Caesarean section even after a course of medication to minimize the risk to the child.
Relapse of genital herpes in the last stages of pregnancy without drug treatment can lead to:
- congenital abnormalities in an infant,
- abortion of pregnancy and fetal death,
- pathologies of the placenta, which prevents the child from receiving nutrients,
- intrauterine infection.
How to reduce relapse
Measures to reduce the incidence of genital herpes should be taken after the onset of remission. How often unpleasant symptoms appear will directly depend on the state of the immune system. To maintain immunity, you need to eat right, usually doctors prescribe a diet or give basic recommendations for the coming months after a relapse.
It is also recommended to consume more vitamins, regularly stay in the fresh air, give preference to moderate physical activity and sleep for at least 7 hours. It is necessary to carefully monitor the state of your health, avoid hypothermia.
To prevent genital herpes, general restoratives may be recommended.
They are selected based on individual characteristics. Doctors often recommend drinking tincture of Eleutherococcus. Particular attention is paid to genital hygiene and the selection of underwear. Preference should be given to natural materials, cotton is the best option. Clothing should not constrain movements, it is better to choose a convenient and comfortable fabric.
To prevent self-infection, you must adhere to the rules of personal hygiene. They include washing hands (in the presence of rashes, this procedure is carried out many times more often), using different towels for the corresponding parts of the body and regular showering.
Maintaining a healthy lifestyle and observing the rules of personal hygiene will help you forget about genital herpes for a long time and enjoy life without fear of relapse.
Herpes Relapse in Men
Relapse of genital herpes is a periodic exacerbation of the disease, which is manifested by the usual symptoms.
In men, a relapse of genital herpes can occur in several forms:
- An acute picture of relapse. It is characterized by the presence of the same vivid signs of the disease, as with the first manifestation of herpes. On the genital area, skin lesions develop in the form of sores with accumulated exudate. At the beginning of the development of the pathological process, the man notes the appearance of burning and severe itching in the penis, redness gradually appears. After a few days, the sores burst on their own, after which a crust appears, which after some time disappears. This form of relapse occurs in every fifth man.
- An atypical picture of relapse. This form of recurrent infection is most often accompanied by the development of itching and redness, rashes are often absent. A similar form of the disease is diagnosed in every second patient.
- Abortive picture of relapse. A form of this type of character for patients who have previously resorted to antiviral therapy or have been vaccinated against herpes virus infection. Relapse is expressed as the appearance of a red spot, which is accompanied by itching and in itself disappears after a few days. The abortive form is characterized by the absence of typical rashes.
- Asymptomatic picture of relapse. Signs of a viral disease do not appear, sometimes slight redness in the genital area may be observed.
Relapse of hypertension (genital herpes) in patients with ongoing HIV is accompanied by a more pronounced clinic and frequency.
On average, exacerbation of GH every 8-12 weeks was observed in patients from this category.
Moreover, herpes was more often diagnosed already at the third stage of HIV pathology.
What are the frequent relapses in genital herpes?
The recurrence rate is due to several factors. The most significant of them is the state of immunity.
Herpes is among the opportunistic infections. This disease is often exacerbated by HIV. Localization of rashes is also important. Most often, anal herpes recurs.
Provoking factors can be:
- serious illness
- surgery or injury
- relocation to less favorable climatic conditions
- infection with concomitant STDs during unprotected sex
Genital herpes recurs much more often than labial herpes (on the lips). Often this happens for no apparent reason.
Severe exacerbations are observed with:
- organ transplant
- stem cell transplantation
- radiation therapy
- long-term use of immunosuppressants or glucocorticoids
Manifestations of recurrent genital herpes
Relapse is a periodic exacerbation of the disease, characterized by the appearance of familiar symptoms in a somewhat worn out or full form. With cold sores, skin lesions appear from time to time that can release the virus into the environment.
Relapsing herpes can have several clinical forms, the symptoms of each of which manifest themselves in different ways.
Find out what drugs are available for asthenozoospermia and what other treatments can be effective?
Relapses of genital herpes in women
In women, relapses of herpetic infection can have a diverse frequency, manifesting from once a year to 4-6 or more often.
Herpetic infection, which manifests itself no more than 3-4 times a year, while the clinical picture of the disease is moderate, has the most favorable prognosis.
If genital herpes and its relapses are frequent - every 1-2 months, a serious violation of the functioning of the immune system should be considered, consultation of an immunologist is recommended.
In women, symptoms of relapse of HSV (genital herpes) can manifest as blisters in the area of:
- vaginal mucosa
- groin hips
Patients often complain of pain during urination and notice unusual vaginal discharge.
A relapse of herpes can be accompanied by an eruption in the vagina, which heals within three weeks.
Inflammation of the cervix can also be a sign of genital herpes.
Particular care must be taken by patients during pregnancy.
In addition, it is necessary to consider what provoking factors exist that affect the functioning of the immune system and, thereby, leading to a new outbreak of herpes.
These should include:
- Menstrual cycle. In some cases, the onset of menstruation can cause an exacerbation or relapse of a herpetic infection.
- The period of pregnancy or lactation. Hormonal background affects the functioning of the immune system, which can lead to a relapse of the disease.
- Artificial abortion.
- The use of hormonal drugs, the setting of intrauterine contraceptives (IUDs).
Relapse of herpes in a woman increases the risks of the following conditions:
- Infection of the sexual partner, which can lead to re-infection after therapy.
- The spread of the infectious process to other parts of the body.
- In the presence of immunodeficiency, it is possible to maintain the clinical picture for up to 4 weeks or more.
- Damage to the pelvic organs, the development of the inflammatory process of the cervix, vagina.
- The formation of atypical cells (malignancy) of the cervix with flowing herpes and HPV.
- Violation of the reproductive system, infertility.
Symptoms of recurrence of genital herpes
In general, the symptoms of relapse are the same as those of the initial infection. But there are some features.
Clinical signs are usually less pronounced. The exception is when severe immunodeficiency occurs. In addition, a prodromal period is usually present before relapse.
In a place where rashes appear in a day, the patient feels a burning sensation, itching or tingling. Moreover, the general condition is usually not violated. There is no fever and malaise.
In 70% of patients, symptoms of genital herpes during relapse are so mild that they do not even notice an exacerbation. But for some, the symptoms are quite pronounced. Rashes appear in the anogenital area.
They look like bubbles with liquid. Opening up, they leave behind erosion. They dry out and form crusts. In their place, hyperpigmented spots form. Healing rashes can last with a relapse of herpes for about 2 weeks. Stains last longer - sometimes several months.
Homosexuals and women who have anal sex can have anal herpes. In another way, it is called herpetic proctitis.
The rectum can be affected to a depth of 10 cm. Painful ulcerations form on its mucosa.
During relapse, patients complain of tenesmus - false urge to defecate.
With genital herpes, lymph nodes often enlarge.
Manifest clinical form
In the presence of this form of herpes in a man, the disease proceeds in the same way as it did at the first manifestation. Bubbles appear on the skin, then turning into erosion and ulcersHowever, in this case, all manifestations occur only on one side of the body or penis. When the disease is just beginning to develop, the man notes a burning sensation, pain in the inguinal region, an irresistible desire to scratch the genitals to get rid of the itching.
The skin in the place where herpes appears is swelling and reddening, and then covered with small bubbles with a clear liquid inside. Soon, the fluid will become cloudy and turn into pus. A few days after suppuration, the vesicles will burst, and in their place the skin will become covered with crusts that will soon fall away, leaving dark spots in their place. This form of genital herpes occurs in every 5 patients.
Diagnosis in the treatment of genital herpes
Diagnosis is an important stage in the treatment of both exacerbation of a viral infection and its relapse.
Laboratory testing should be performed for patients with the first episodes of genital herpes (and atypical relapses).
In order to confirm the diagnosis and determine the type of virus involved.
Such diagnostics can provide predictive information regarding the course of the virus.
For example, HSV-2 often provokes relapses of genital herpes than HSV-1 infections.
Approximately 70–90% of patients with symptoms of genital infection have HSV-2, and only 20–40% of patients with a similar disease have HSV-1.
Serological testing for herpes virus, i.e. testing for antibodies to HSV-1 or HSV-2, is not recommended as a routine study.
Antibodies against herpes usually develop from two to six weeks, and sometimes this period can take several or more months.
Thus, patients with new infections can be negative for antibodies.
A positive serological result may indicate that the patient previously had an asymptomatic infection.
But such a result, as a rule, does not affect the further principle of therapy.
Serology may be useful in certain circumstances.
For example, to check if a pregnant woman has antibodies to the herpes virus if her partner has relapses.
In general, it is not difficult for a doctor to diagnose genital herpes, and specific rashes in the genital area contribute to this.
In some cases, with a relapse of genital herpes, the doctor may prescribe tests.
To confirm the diagnosis, they resort to a polymerase chain reaction.
Blood, smears from the urethral canal, urine, seminal fluid can be used as biological material.
PCR in the diagnosis of pathologies of an infectious nature is considered the "gold standard".
The analysis allows you to directly detect the DNA of the virus and establish the fact of infection before the onset of clinical signs.
Relapse tests for genital herpes
With a relapse of herpes, confirmation that it was herpes that provoked the symptoms is usually not required. The diagnosis is clinically established.
It is not difficult, especially if:
- there is an anamnesis data indicating that the patient is already a carrier of the herpes virus, and he had relapses earlier
- herpes occurs in a classic clinical form - there are bubbles with fluid in the genital area
There are complex clinical cases. Then laboratory confirmation of relapse is performed. For this, a blood test for antibodies is used.
IgM does not always appear. Therefore, the main way to confirm the fact of exacerbation of genital herpes is to measure the level (titer) of IgG in dynamics.
These immunoglobulins may be present in the blood continuously. However, with relapse, their titer increases.
It is also necessary to find out the reasons why the exacerbation occurred. For this, the patient passes an immunogram. He also undergoes an immunologist consultation.
After all, the most common cause of relapse is a malfunction of the immune system. Without this factor, genital herpes can not bother a person for years and decades, endlessly in a latent state.
With frequent relapses, the doctor may take HIV tests. Like herpes, it is transmitted sexually. Therefore, these infections are often combined.
HIV aggravates the course of genital herpes, increases the frequency of relapses. Because it causes a decrease in cellular immunity.
Atypical clinical form
Suffering from the atypical form of herpes, a man notes only itching, swelling and redness of his skin. The skin and mucous membranes may crack - in which case the wounds will disappear after a few days.
Occasionally, with an atypical form of the disease, blood-red pus can accumulate in the vesicles.. This form occurs in every second patient of venereologists.
Herpes relapse treatment: what drugs are prescribed
What is the most effective treatment for relapse of genital herpes?
The most commonly prescribed drugs for herpes therapy are Valaciclovir and Aciclovir.
Valaciclovir, has a similar active component, which, when ingested, is rapidly transformed into acyclovir.
It is an antiviral medicine that can be used to treat infections. Herpes simplex and Herpes zoster, as well as in relapsed diseases.
Valacyclovir is as effective as Acyclovir in the same range of indications.
But it has a simpler dosage regimen and is more effective in exacerbating herpes infections and relapses.
Due to the improved bioavailability of Valaciclovir compared to Acyclovir, the first drug is often recommended for patients with exacerbation of HSV or the development of a recurrent infection.
Valacyclovir is effective in the treatment of HSV infection of the first episode in a dose of 500-1000 mg to two times a day.
Also, in the treatment of recurrent HSV infection at a dose of 500 mg twice a day, if therapy is started within the first 24 hours after the first signs of a viral disease appear.
Valacyclovir (the second name of the drug Valtrex) is also used to prevent viral infections in people with weakened immune systems.
For example, it is prescribed to patients undergoing chemotherapy or undergoing organ / tissue transplantation.
Continuous treatment with Valaciclovir may reduce the incidence of symptomatic episodes of genital herpes.
Patients may regularly experience recurrent genital herpes, for example, six or more episodes per year.
They can use Valaciclovir as a prophylactic to reduce the impact of the disease and provide a sense of control of the virus.
Currently, Valtrex (Valacyclovir) is considered the only drug that can stop the signs of relapse of genital herpes in three days of admission.
Clinical trials of the drug showed its ability to reduce by almost 85% the risk of recurrence of herpes with daily medication.
Without treatment, symptoms of genital herpes can last up to 3 weeks.
Treatment with Valaciclovir or Acyclovir reduces the healing time, severity and duration of the symptoms of the virus.
Relapse of genital herpes during pregnancy
Herpes is dangerous for the fetus. Therefore, the recurrence of herpes during pregnancy is an unfavorable phenomenon. But still it is less dangerous than primary infection.
Significantly reduced the risk of transmission of the disease from mother to child. With primary herpes, the probability of infection of the fetus reaches 50%.
With relapse, it is less. If there are no rashes on the genitals, but do not exceed 4%.
But still there is a risk of complications:
- early spontaneous abortion
- premature birth
- low birth weight
With relapses of herpes in pregnant women, acyclovir prophylaxis can be carried out. Studies show that it is safe.
Compared with the control group, acyclovir in the first trimester does not increase the risk of the most common fetal malformations. In some cases, caesarean section is required to prevent fetal infection.
It is necessary if:
- there is a primary infection with herpes, with an active course of infection at the time of delivery
- recurrence of herpes if there are rashes on the genitals
In these cases, a cesarean section is necessary, regardless of whether acyclovir has been used. But its timely appointment often allows you to quickly stop the recurrence of herpes during pregnancy. Therefore, the drug significantly reduces the number of caesarean sections, increasing the number of women with herpes infection who have given birth to a child in a natural way.
Interrupted Clinical Form
This form of herpes recurrence is also called abortive, and manifests itself in patients previously treated with special drugs or a vaccine. The disease can manifest itself in the form of a spot that turns red and itches, and disappears after 2-3 days. The abortive form is always characterized by a complete absence of vesicle rashes.
How to take Valacyclovir for genital herpes
Recommendations on the dosage of Valacyclovir in the treatment of genital herpes and relapses vary, the treatment regimen depends on the course of the disease, as well as the general condition of the patient.
At the first episodes: Valaciclovir 500 mg twice daily for seven days, or longer.
If new elements of the rash appear or the old lesions do not completely heal, an increase in dosage is possible in agreement with the doctor.
For recurring episodes (episodic treatment): Valaciclovir 500 mg twice daily for three days.
For the prevention of relapse (suppressive treatment): maintenance doses of Valaciclovir 500 mg daily.
Recommended only if confirmed by HSV in laboratory testing.
Dosage may be increased to 500 mg twice daily or 1 g once daily for patients who continue to experience multiple relapses.
This dosage must be approved by the attending physician individually.
When using Valacyclovir, side effects may develop:
Common adverse reactions:
- nausea and vomiting
Unusual adverse reactions:
- breathing problems
- feeling of excitement
Rare side effects:
- stomach discomfort
- defecation disorder (diarrhea)
Very rare side effects:
- anaphylactic reactions
- blood changes, including thrombocytopenia, leukopenia
- tremor, spontaneous muscle movements (ataxia), speech disorders (dysarthria), cramps
Valacyclovir is not recommended in such cases:
- allergic to any of the ingredients of the drug
- over 65 years old
- severe immunodeficiency
- impaired kidney and liver function
Treatment for relapse of genital herpes
With a relapse of genital herpes, the symptoms are usually weaker than with the initial infection. Therefore, the course of treatment is shorter. It is allowed to use not only systemic, but also local preparations.
The standard scheme involves the appointment of acyclovir. It is used at a dose of 200 mg, 5 times a day. The course lasts 5 days.
Valaciclovir may be used. It has a similar effectiveness. But more convenient to use. The course also lasts 5 days. But the drug is used only 2 times a day. Single dose - 0.5 g.
Alternative regimens involve the use of topical forms of drugs. They are applied to the genitals - in those places where there are rashes. Acyclovir cream may be used. It is available in various dilutions: there are 3% and 5% cream.
The second is more effective, as it contains a large concentration of the active substance. Use this cream 5 times a day. The course of treatment can last from 5 to 10 days. It should be used until symptoms disappear.
Other drugs are also used that do not contain acyclic nucleosides.
The following schemes are used:
- vidarabine in the form of a 10% gel - a course of 7 days, 4 times a day
- riodoxol in the form of an ointment (concentration of 0.5% or 1%) is prescribed for up to 10 days
- glycyrrhizic acid is applied to the genitals and sprayed into the vagina 6 times a day, for up to 10 days
The cure can be established without analysis. Based on clinical signs alone. If there are no more symptoms, this means that the exacerbation of herpes has ended and the disease has entered a latent phase.
Serological diagnostics may also be used. The titer of antibodies is determined.
Successful relief of exacerbation is indicated by a decrease in the number of immunoglobulins within 1-2 weeks.
Relapses of genital herpes: which medicine to choose?
Acyclovir and Valacyclovir are the most studied antiretroviral drugs for the treatment of genital herpes.
Studies of Acyclovir confirmed the conclusion that a dose of 200 mg five times a day for 7-10 days is effective in reducing the incidence of genital herpes and stopping its symptoms.
The increased bioavailability of Valacyclovir allows you to take the drug three times a day at a dose of 1000 mg for 5 days. Valacyclovir accelerates the relief of pain and offers easier dosing while maintaining the effectiveness and safety of therapy.
Recent studies have shown that treatment with Valaciclovir reduces the chance of transmitting Herpes simplex type II virus by 50% and inhibits the release of the virus from the genital tract.
In patients with HIV-positive status, a dose of 1000 mg twice a day was comparable to 200 mg of Acyclovir five times a day in the treatment of one episode of GH (genital herpes).
Whereas 500 mg twice daily was superior to placebo in the prevention or delay of relapse.
Two drugs have similar safety profiles.
Famciclovir (Famvir) can be considered as an analogue of both drugs.
With the development of relapse of genital herpes, the drug is usually prescribed in a dosage of 250 mg twice a day, for five days.
The bioavailability of the drug is 75-78%.
During therapy, the patient must abandon sexual intercourse and do not resume intimacy until the clinical signs of the disease have stopped.
Valacyclovir for relapses of genital herpes
The first drug to be highly effective against the herpes virus was acyclovir. But it has a number of disadvantages. After that, other acyclic nucleosides appeared.
Often with relapse of genital herpes, valaciclovir is used.
The treatment regimen provides for the appointment of this drug at 500 mg, 2 times a day, 5 days course.
Compared with acyclovir, it has several advantages:
- 3-5 times higher bioavailability (better absorbed into the blood)
- long-term action - the drug can be taken less often, which is convenient for the patient and increases compliance (a person does not forget to drink pills on time)
- with oral administration of valaciclovir in the blood, drug concentrations are comparable to intravenous administration of acyclovir
- can be prescribed regardless of food, while taking acyclovir with food reduces its absorption and, therefore, effectiveness
Valacyclovir quickly begins to act.
A high concentration in the blood is created after 30-60 minutes. The drug also has advantages over famciclovir. It is 100 times more active on the DNA polymerase of the herpes virus.
What to do with frequent or not very relapses of genital herpes in men?
So, the next exacerbation of genital herpes is already very close, which means that something needs to be done. To relieve pain or temperature, you can take an ibuprofen or paracetamol tablet. A cold heating pad or ice applied to an itchy and painful part of the body will also help alleviate the condition.
However, both a heating pad and ice gently wrap in a clean cotton napkin so as not to damage the vulnerable tissues and introduce another infection. The genital baths will help to get rid of the vesicles and ulcers more quickly: 2 teaspoons of salt should be dissolved in a liter of water and cooled to room temperature. But with hot baths it is worth the time: high temperatures will only contribute to strengthening the symptoms of the disease, and stagnant water carries a slight, but still a risk for infection of other body tissues.
One of the effective remedies for all types of herpes is acyclovir - a substance that affects only cells infected with the virus, without affecting healthy cells in the body. If during the initial course of the disease, acyclovir is prescribed to alleviate symptoms, reduce the spread of the virus and the degree of skin damage, prevent serious neurological damage, then with a relapse of the disease, it can only reduce the duration of the course of the exacerbation by a day or two.
A more effective way to achieve remission is the regular and constant use of acyclovir: without affecting healthy cells, the substance constantly “guards” the body and destroys its affected elements, preventing the disease from developing further. Taking acyclovir daily, it is possible to eliminate more than 70% of repeated exacerbations, and in some of these patients relapses are completely absent throughout life.
Alas, this kind of oppression therapy is advised only occasionally and only to those patients in whom relapses occur, on average, every 2 months: such therapy is quite expensive, it cannot be neglected, and the patient’s normal life may change somewhat.
Sometimes patients develop resistance to the drug, which may subsequently cost them their lives. Most often, resistance to acyclovir appears in patients with weakened immunity due to:
- HIV infection
- organ transplantation
- oncological diseases.
Herpes infection indicator
The virus responsible for herpes is defined as “neurotropic” and “epidermotropic”.
In fact, it is at the level of the nerve ganglia, where it remains "inactive" and hidden.
With certain events, the body's defenses are weakening - a long period of stress, taking medications, hormonal disorders.
The virus reactivates, causing the appearance of vesicles and other symptoms of herpes.
Therefore, it is important to learn how to determine the subsequent relapse of the disease and its duration.
So, some studies have been conducted regarding the recurrence of herpes, of which one can distinguish an analysis of scientists from Seattle under the leadership of D. Schiffer.
During the study, specialists studied in detail the clinical data of the infection of nearly 400 patients and their laboratory tests conducted to identify the DNA of the virus, as well as the number of T cells in the genitourinary system.
T cells, or as they are called T-lymphocytes, were taken as an indicator of the infectious process.
A similar solution is due to the fact that T cells have the ability to quickly recognize an infected cell by the viral antigen formed on its surface.
The task of T-lymphocytes is to recognize the pathogen as early as possible and begin to eliminate it, until it manifests itself in the form of lesions on the skin.
Maintenance doses of drugs for genital herpes
For the prevention of relapse, maintenance doses of acyclic nucleosides are used. These doses are less than therapeutic. But a person receives them constantly.
The main indication is recurrent herpes. That is, a condition in which the frequency of exacerbations exceeds 6 per year.
Other situations in which maintenance therapy may be prescribed:
- patient's reluctance to infect herpes with a sexual partner
- severe exacerbations of herpes
- immunodeficiency conditions, including HIV
For maintenance therapy, several drugs may be prescribed.
According to the protocol for the management of patients with genital herpes, the following can be used:
- acyclovir - 2 times a day for 0.4 g
- Valaciclovir - 1 time per day, 0.5 g each
The second scheme is more effective. Therefore, valaciclovir is used more often. It is also more convenient for the patient. Because it is applied not twice, but 1 time per day.
Often patients ask how harmful the constant use of acyclovir analogues is to prevent the recurrence of herpes. Most likely, this is not harmful. At least, studies evaluating the patient’s health status after 1 year of regular use of acyclovir did not reveal any serious or irreversible side effects and health effects.
There are cases when continuous suppressive therapy was carried out for more than 15 years in a row. But if the patient does not want to take the drugs inside, external treatment can be used.
Glycyrrhizic acid is used. She is prescribed 2 times a day.
Women use it in courses of 10 days. The drug is used in the second phase of each menstrual cycle.
The prevention of the disease must necessarily include consultations with a specialist, where the doctor will tell you how to avoid exacerbation, not to transmit the virus to your partner and others, and also not to get them from relatives. However, often even doctors do not know anything about effective measures to prevent relapse.
Unfortunately, the vaccine will not be able to fight against genital herpes already settled in the body. But the constant use of acyclovir significantly reduces the risk of relapse.
A condom does reduce the likelihood of contracting and transmitting the disease, but it cannot offer any guarantees. Therefore, loyalty to one sexual partner and caring for one’s health should become the cornerstones in the struggle for one’s health.
Genital herpes is an infection with which a man will have to live for many years.: Having visited once, she will settle in the house forever. Despite the fact that herpes can significantly disrupt the regularity of the patient’s life, it can be suppressed and must be controlled. Only an active position in relation to one's own health will help a man live a full and happy life!
Learn how frenulotomy of the frenum of the penis is performed and what the pathology of the short frenum is fraught with.
Find out how a short bridle in men looks and in what cases it is worth resorting to treatment, find out on this page.
Prevention of genital herpes: how to minimize relapses
Women are more susceptible to herpetic infection, they are more often infected by the man.
In principle, this applies to all types of STDs.
So, the risk of acquiring HSV from a man is almost 15%, when the transmission of the virus from a woman is only 4%.
As a prevention of relapse of HSV (genital herpes), first of all, antiviral therapy is considered, which reduces the risk of re-development of symptoms by 50%.
The second point is the use of contraception (condoms) during sexual contact, which can reduce the risk of infection by almost 80%.
Prevention of recurrence of genital herpes
Relapses occur in almost everyone. But 70% of people do not even notice them. Because the elements of the rash occupy an area of 1-2 square centimeters. And they are not accompanied by pronounced sensations.
But if the relapse is difficult, there are some reasons for this. And they usually consist in a poor state of immunity. Therefore, to reduce the number of exacerbations, often in combination with chemotherapy, immunomodulating therapy is used.
The doctor prescribes drugs to strengthen the immune system. After this, the body itself begins to actively fight the virus.
Barrier contraception as a prevention of genital herpes
What to do so that after sex there is no relapse of genital herpes?
The answer is simple: defend yourself!
Latex products in the form of condoms provide fairly good protection.
The viral pathogen is not able to penetrate synthetic material.
A female condom also provides good protection.
In addition, it does not allow contact with the external genitalia of a woman, which further reduces the risk of infection.
The use of barrier methods of contraception in conjunction with antiviral drugs provide quite good protection against infection.
Vaccines may also be used to prevent relapse.
The most famous drug is "Vitagerpavak", aimed at stopping the herpes virus of the first and second type.
Where to go with a relapse of herpes?
In case of recurrence of genital herpes, contact our clinic with an experienced dermatovenerologist.
We will help:
- quickly remove symptoms
- reduce the duration and severity of relapse
- prevent complications (meningitis, sciatic nerve neuritis and others)
- establish the cause of frequent or severe relapses
The doctor of our clinic will select for you treatment that will not only cure another exacerbation of herpes. It will avoid relapses in the future due to the normalization of the state of the immune system.
For relapses of genital herpes, contact the author of this article, a dermatovenerologist in Moscow with many years of experience.
Herpes and pregnancy
Herpetic infection is a disease that can be transmitted to the fetus.
If a woman becomes infected during pregnancy, the risk of transmitting the baby's virus reaches 60%.
In case of recurrence of genital herpes, the risk of transmission to the fetus during pregnancy is no more than 5%.
To minimize the risks of intrauterine infections during pregnancy, you need to abandon intimacy, in which a condom is not used.
Including oral caresses and anal intercourse.
In the third trimester, antiviral drugs can be recommended that will stop the symptoms of herpes and avoid cesarean section.
For relapses of genital herpes, contact the author of this article, a dermatovenerologist in Moscow with many years of experience.